News & Stories

In a new study, scientists at The Hong Kong University of Science and Technology (HKUST) have revealed that most T cell epitopes known to be targeted upon natural infection are seemingly unaffected by current SARS-CoV-2 variants. In their latest research, the team compiled and analysed data from 18 immunological studies of T cell responses involving over 850 recovered COVID-19 patients from across four continents who are well-distributed in age, gender, disease severity and blood collection time. They demonstrated that T cells in these patients targeted fragments (epitopes) of almost all of the virus' proteins, including the spike protein that is a main target of many existing vaccines. As an important finding, based on analysis of over 850,000 SARS-CoV-2 genetic sequences from around the world, most of these epitopes appeared to be unaffected by the current variants of concern.

It is challenging to analyze proteins at low concentrations, especially for those in a mixture of various conformations such as intrinsically disordered proteins (IDPs). A research team led by Prof. HUANG Jinqing, Assistant Professor of Department of Chemistry at The Hong Kong University of Science and Technology (HKUST), has developed optical tweezers-coupled Raman spectroscopy that can directly probe the structural features of alpha-synuclein, an IDP closely linked to Parkinson’s disease, at the physiological concentration by focusing on individual protein molecules. 

Liquid Crystals (LC) are widely deployed in display technology and optical fibres. From smartphones in your pockets to large screen TVs, LCs are everywhere, as this special state of matter has been found in colorful soap bubbles as well as certain living tissues.

Surgical masks are effective in blocking airborne carcinogens, reducing cancer risks such as lung cancer and leukemia.

Rapid and accurate communitywide detection is crucial in curbing COVID outbreaks. While the Government has been busy expanding Hong Kong’s overall testing capacity, HKUST recently took the initiative of putting concerned students and staff members’ minds at ease by offering a convenient, on-campus testing service. 

A closet has been developed to kill 99.99% of the bacteria and viruses on the garment inside within a minute.

Does being nice pay off at the virtual bargaining table?

An inter-disciplinary team of researchers led by Prof. Qian Peiyuan, Chair Professor at the Hong Kong University of Science and Technology (HKUST)’s Department of Ocean Science and Division of Life Science has unraveled how a novel microbial small molecule released by Streptococcus mutans (S. mutans) – a bacterium commonly found in the human oral cavity – is connected to dental caries development using a synthetic biology approach, offering new insights to the health impact of the human oral microbiota and facilitating future research on the prevention of tooth decay. The research findings were recently published in the prestigious scientific journal Nature Chemical Biology and reported by Nature as one of the research highlights.